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A low-tech problem troubles the high-tech world of digital pathology imaging: There are no reliable standards for the quality of digitized tissue slides comprising the source material for computers reading and analyzing vast numbers of images. Poor-quality slides get mixed in with accurate slides, potentially confusing a computer program trying to learn what a cancerous cell looks like. Researchers are trying to fix this, sharing an open-source quality control standard.

A low-tech problem troubles the high-tech world of digital pathology imaging: There are no reliable standards for the quality of digitized tissue slides comprising the source material for computers reading and analyzing vast numbers of images. Poor-quality slides get mixed in with accurate slides, potentially confusing a computer program trying to learn what a cancerous cell looks like. Researchers are trying to fix this, sharing an open-source quality control standard.

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Researchers have discovered novel genes and pathways related to early stages in the development of celiac disease and the ongoing inflammation and comorbidities associated with the condition.

Researchers have discovered novel genes and pathways related to early stages in the development of celiac disease and the ongoing inflammation and comorbidities associated with the condition.

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Behavioral problems in young people with severe antisocial behavior -- known as conduct disorder -- could be caused by differences in the brain's wiring that link the brain's emotional centers together, according to new research.

Behavioral problems in young people with severe antisocial behavior -- known as conduct disorder -- could be caused by differences in the brain's wiring that link the brain's emotional centers together, according to new research.

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Bioengineers have developed a new method for Bulk RNA Sequencing that combines the multiplexing-driven cost-effectiveness of a single-cell RNA-seq workflow with the performance of a bulk RNA-seq procedure.

Bioengineers have developed a new method for Bulk RNA Sequencing that combines the multiplexing-driven cost-effectiveness of a single-cell RNA-seq workflow with the performance of a bulk RNA-seq procedure.

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The Time to Reduce Mortality in ESRD (TiME) trial was a large pragmatic trial demonstration project designed to determine the benefits of hemodialysis sessions that are longer than many patients currently receive. The trial was conducted through a partnership between academic investigators and 2 large dialysis provider organizations using a highly centralized implementation approach. Although the trial accomplished most of its demonstration project objectives, uptake of the intervention was insufficient to determine whether longer sessions improve outcomes.

The Time to Reduce Mortality in ESRD (TiME) trial was a large pragmatic trial demonstration project designed to determine the benefits of hemodialysis sessions that are longer than many patients currently receive. The trial was conducted through a partnership between academic investigators and 2 large dialysis provider organizations using a highly centralized implementation approach. Although the trial accomplished most of its demonstration project objectives, uptake of the intervention was insufficient to determine whether longer sessions improve outcomes.

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A study reveals that neurons in the motor cortex exhibit an unexpected division of labor, a finding that could help scientists understand how the brain controls the body and provide insight on certain neurological disorders.

A study reveals that neurons in the motor cortex exhibit an unexpected division of labor, a finding that could help scientists understand how the brain controls the body and provide insight on certain neurological disorders.

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Researchers tested bacteria commonly found inside homes on samples of drywall coated with antimicrobial, synthetic latex paints. Within 24 hours, all bacteria died except for Bacillus timonensis, a spore-forming bacterium.

Researchers tested bacteria commonly found inside homes on samples of drywall coated with antimicrobial, synthetic latex paints. Within 24 hours, all bacteria died except for Bacillus timonensis, a spore-forming bacterium.

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Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered organisms.

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells. The research dramatically expands the chemical, physical and environmental cues engineers can use to prompt programmed responses from engineered organisms.

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In a proof-of-principle study in mice, scientists report the creation of a specialized gel that acts like a lymph node to successfully activate and multiply cancer-fighting immune system T-cells. The work puts scientists a step closer, they say, to injecting such artificial lymph nodes into people and sparking T-cells to fight disease.

In a proof-of-principle study in mice, scientists report the creation of a specialized gel that acts like a lymph node to successfully activate and multiply cancer-fighting immune system T-cells. The work puts scientists a step closer, they say, to injecting such artificial lymph nodes into people and sparking T-cells to fight disease.

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Using network science -- part of a larger mathematical field called graph theory -- a professor mapped long range atomic forces onto an incredibly complex graph to simulate macroscopic material behavior.

Using network science -- part of a larger mathematical field called graph theory -- a professor mapped long range atomic forces onto an incredibly complex graph to simulate macroscopic material behavior.

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